Mildronate

With 256 inventions and over 900 patents and patent applications Ivars Calvin is one of the most productive scientists in medical biochemistry. This has the Latvians now introduced a nomination for the European Inventor Award in the lifetime achievement category. Above all, the heart medicine Meldonium, marketed under the name Mildronate, has led the Inventor Award jury on its decision. "More than two million people are currently being treated with it," says Calvin.

The enormous productivity of the scientist seems to even more remarkable. While Calvin was able to go in 1979 as a postdoctoral fellow at the Ludwig-Maximilians-University, but ultimately the price for the privilege was too high. His wife and two young daughters were not allowed to join him in Munich. The talented young scientists returned to the Soviet Union, where he tried Mildronate not to let that stop you from scarce resources , who developed drug molecules for Organic Synthesis since the 1970s at the Latvian Institute recalls. So it went on until after careful consideration of the production of organic compounds in the laboratory, and then rushed to check these for their practicality in experimental animals.

Expensive screenings bypasses the researchers

Normally, it is common in the pharmaceutical industry to test thousands and thousands of substances in high throughput screening, and then the best candidates to optimize step by step. This process, which takes a lot of time and money, Calvin bypasses still.

"Others think I'm crazy. But I've always worked - not only with his hands, but also with the brain, "he says with a wink. "I start my projects well thought out. And I believe that God helps me also to end it. "

This was also his credo in developing Mildronate. The drug comes about in the coronary heart disease is used or after a heart attack. These extremely frequent cardiovascular-suffering the heart muscle due to atherosclerosis (hardening of the arteries) is no longer a sufficient blood supply. The tissue is increasingly damaged by toxic degradation products.

Mildronate directs the metabolism of stressed muscle cells from new. Through the active formation of the amino acid carnitine is inhibited, thus inhibited the oxidation of fatty acids. Thereby the cells remains more oxygen, also less degradation products accumulate. Such relieved, the heart can handle the lack supply better and fueling glucose as an energy supplier. Go here to our official site  http://www.mildronate.me/

Best Eye cream

A routine skin care is not complete without an eye cream. Using an eye cream or gel is essential to calm, reduce swelling, eliminate dark circles and to help fight the aging process. Many brands claim to have the elixir of youth in their creams , gels and serums eye treatment but has a price, both financial and possible harmful side effects. So in an attempt to use beneficial natural ingredients and make a natural cream Here 's a basic but effective to protect, moisturize and strengthen the skin around the eyes recipe.

Benefits of Eye Cream

Improves skin texture
It is rich in antioxidants
Reduces swelling
Reduces dark circles
Soothes and protects
hydrates
Nourish
Treats wrinkles and fine lines
Prevents premature aging
Repair sun damage
It improves the appearance of the skin of the eyes
Improves skin discoloration
Treats skin disorders

The skin around the eyes is more delicate and thinner than the skin elsewhere on the face or body, with the exception of the back of the hands. The eye area is likely to develop signs of aging and sagging as we mature. Facial expressions such as smiling and laughing (lines) and are a natural cause of the lines around the eyes that can not and must not avoid. These lines add character and make us human, after all.

These two ingredients are one of the best in terms of benefits to the skin and this eye cream is a fantastic natural product without chemicals or synthetic fragrances.
A test is always recommended when using any product for the first time or if you have very sensitive skin.
You can customize this recipe if you wish by adding essential oils according to the needs of your skin . Shop carefully the amounts and portions.
Evening primrose oil is another big carrier or base which is excellent for anti-aging oil, so feel free to incorporate it . It could fill the container with half coconut oil, and the other half with evening primrose oil.
https://muhammadhassun.wordpress.com/2016/10/25/intensive-best-eye-cream/



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The super pizza how ot eat it

Fatigue, lack of time ... some is why there are some nights where a "flême" we really cooking, which often pushes us to choose ... The super PIZZA ! No luck, the pizza is a "flat" whose caloric addition can be heavy (up to 1500 kcal pizza with 4 cheeses of the restaurant, even more if you water the olive oil!). Here are some tips offered by Dr BonneBouffe to make you enjoy the pizza without exploding the calorie counter !

HOW TO EAT PIZZA WITHOUT FEELING GUILTY?

# 1. REDUCE THE SIZE OF THE PIZZA
Come on, it's decided: we eat a pizza tonight! ... But beware: no need to put a whole pizza per person either! Prefer a small pizza or 1/4 of a large pizza. In fact, the trick to enjoy your favorite foods while keeping a healthy diet lies in the quantities !

And this applies to all foods! Reduce the portion in favor of healthier foods , such as vegetables , for example!

# 2. CHOOSE THE BEST PIZZA

Before you throw on a the super pizza, think and doing it right ! Opt for example for pizza with vegetables (eg sun vegetables) instead of choosing one or salami pizza with four cheeses, which tend to be fatter and more caloric .

3. INCORPORATE VEGETABLES

As advised by the site Hard to Swallow , you have to do with the idea that "  the pizza is not an accompaniment, not a meal all by itself ". Therefore reduce the portion of your pizza will incorporate a good plate of crudités. And yes, it will allow you to reduce the number of calories consumed while enjoying the benefits of vegetables .

# 4. EAT SLOWLY

Eating slowly is important. This allows, among other things, control his calorie intake, monitor the signals from her body and truly enjoy what you are tasting or easting.

The trick of DrBB: Eat your pizza with cutlery! And yes because eating pizza with cutlery (instead of eating with your hands) you will eat more slowly, pushing you to cut small pieces to eat.

# 5. TAKE A FRUIT DESSERT

A healthy diet should be based on compromise : if you fall for a main dish calorie food (eg pizza), opt for something lighter dessert . Choose, for example, fresh fruit or fruit salad to offset the high calorie the super pizza.

# 6. DRINK WATER

Remember: Drinking water is essential , it is advisable for both your line but also for your health . Leave out the sodas hyper-flavored and high-calorie in favor of a glass of water . This will allow you initially to better enjoy your pizza, but also to limit the sugar and unnecessary calories !

# 7. MAKE YOUR PIZZA YOURSELF!

The best option is to eat better to control what you eat . The best way is obviously to prepare yourself a meal . Indeed, you can imagine that a frozen pizza industry will not have the same mineral inputs or the same energy values ​​a the super pizza prepared by you !
As inconveniences to be remedied by making a homemade pizza!

eyebrow threading Tips for best results

The correct form and the arch of the eyebrow can open the eyes of the eyes and create a more youthful appearance. Hair removal and waxing are good ways to maintain an impeccable appearance but a technique called thread is a fast and gives relatively painless way to get the look that sustainable waxing. If you do it yourself or go to a salon, it can shape the eyebrow threading Tips and creating is a new and classic look for anyone - anyone with eyebrows.

Instructions

Formatting

• Take an eyebrow pencil and align vertically on the side of your nose to the corner of the eye (which corresponds to your tear duct). This will be your first point of reference, so make a small mark with your eyebrow pencil to mark the point. If there is hair beyond this place, mark on your nose and remove hair.

• Tilt the same eyebrow pencil to your nose to the iris of the eye and beyond, up to your forehead. This is the arc of your eyebrows. Make a small mark where the liner hit the front as reference point.

• Make a line with your eyebrow pencil on the side of your nose, at the end of your eyebrow and make a small mark. This indicates where your eyebrow should end. Hair beyond this point may be plucked.

• Connect the dots with your eyebrow threading Tips. Run a relatively straight line from the beginning of your brow to the arch and then back down at the end of your forehead. Tweeze the hairs protruding marks.

Threading

• Start by cutting a section of 2 feet of cotton thread. You will use this thread to gently remove hair by the follicle, giving you a sustainable grooming eyebrows.

• Knot the thread ends together to form a circle and hold the wire circle open with your fingers and thumb to make a rectangle.

• Turn the thread by folding the fingers about 10 times to create an X in the middle of your hands. Open and close the fingers on one hand to the X thread closer to your dominant hand.

• Place the thread X next to the hair you want to delete and move your fingers back to remove these hairs. You will need to practice a little, but once you know the movement, it will go fast. Put the hair you've eliminated when shaping eyebrow threading Tips.

Tips & Warnings

To make the process even easier, use a brow template to quickly and easily define your eyebrows. Use eyebrow powder for a softer look. Practice thread on a friend to get the feel of the threading technique.

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How to learn waxing thread

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Agen poker ditempatkan di

Sisanya 26 kartu ditempatkan di tengah.

1. Dapatkan kartu dengan sub warna

terbesar untuk memesan terkecil Spades sekop & gt; hati hati & gt; box diamond & gt; klub Plum

ukuran titik membuat a & gt; K & gt; Q & gt; J & gt; 10 & gt; .. & Gt; 2. 3. untuk memulai penawaran dan kemudian mereka memutuskan untuk truf untuk melihat warna dan sampai poin yang tinggi, yang disebut jas. Jika itu tidak sangat kuat, dan disebut tidak ada raja (no-truf, NT). Bisa juga lewat tangan (Lulus) tidak disebut, atas nama pihak lain untuk menerima tawaran tersebut. Jika Anda dapat menerima panggilan dari warna yang berbeda Click here for more information.

Row tujuh, juga dikenal sebagai permainan Solitaire adalah pertempuran kecerdasan permainan membutuhkan usaha. Game ini ditandai dengan keterampilan perizinan dan melihat bagaimana kartu sebelum mereka dapat membuat kartu sendiri mencakup minimum, dan membiarkan orang lain menutupi sebagian besar kartu menang. Bermain

Setelah perizinan selesai, dengan tangan sekop tujuh kartu pertama keluar, dan untuk menghindari arah kartu waktu rotasi.

Mulai dari kartu rumah secara berurutan (jika pemain lain memiliki nomor tujuh jenis lain dari warna, itu tidak perlu selalu harus bermain). Selama ada di bawah rumah kartu yang berdekatan dari jenis yang sama dengan kartu. Dapat berurutan ke depan (enam angka) atau mundur (delapan angka) kartu.

Jika tangan pemain kartu tidak bisa bermain keluar (jenis kartu saat ini tidak dapat dikeluarkan pada desktop kartu yang berdekatan) akan menjadi "flip." Setiap putaran dari lipatan pertama tidak bisa menutupi A atau K.

Lipat dan kemudian terus turun yang berikutnya, ketika semua pemain akan membagikan kartu setelah yang menentukan hasilnya.

Pemain dapat memilih untuk menutupi jumlah substansial lebih kecil dari poin, atau mengganggu pemain lain dapat menutupi kartu berikutnya. Tetapi jika pemain lain bisa keluar dari kartu, Anda benar-benar tidak bisa lipat. Ketika dilipat, itu tidak bisa istirahat dari perizinan. Misalnya, 1.2.6, maka 6 tidak mencakup pertama, jika 8.JK, pertama 8 tidak bisa menutupi.